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statisticsSingHealth Duke-NUS Researchers Co-Authored a Book on Clinical Research Sample Sizes

Associate Professor Tan Say Beng, Group Director of Research, SingHealth and Senior Associate Dean, Duke-NUS, and Ms Tan Sze Huey, Principal Biostatistician, NCCS co-authored the fourth and extended edition of “Sample Sizes for Clinical, Laboratory and Epidemiology Studies”.

 

Written for medical researchers from all specialties and medical statisticians, the book explains and explores the wide range of considerations necessary to assist investigational teams when deriving an appropriate sample size for their study. This edition includes content on Sample Size Software and the formulae and numerical tables needed to design valid clinical studies.

 Immunotherapy Makes Breakthrough in Breast Cancer
A large scale study involving 902 patients examined the effectiveness of the immunotherapy drug Atezolizumab. Triple-negative breast cancer patients who were treated with immunotherapy and chemotherapy survived 7.2 months without the diseaese progressing, compared to 5.5 months in a chemotherapy-only group.
CPR A Game Changer for Blood Cancer Patients
​Conventional cord blood transplant for treatment of leukaemia or other blood cancers usually require two units of cord blood for adult patients, and has a higher than 30 per cent mortality rate. With a new cord blood expansion technique, Nicord®, fewer than 10 per cent of patients died. More clinical trials are in the pipeline to take leverage on this new technique.
Shedding Light on a Surgical Problem
Klaro, a bendable device with a row of minute LEDs (light-emitting diodes) at its tip was the brainchild of Associate Professor Tan Ngian Chye, Senior Consultant, Division of Surgical Oncology, National Cancer Centre Singapore (NCCS), invented in collaboration with SingHealth Medical Technology Office (MTO), NCCS and SGH surgeons, Vivo Surgical and Panasonic Lighting Europe, to resolve surgical challenge caused by shadows from overhead lights or headlamps.
doctor's prescriptionFirst-of-its-kind Public-Private Partnership in Asia focused on Myopia
SNEC, SERI and Johnson & Johnson Vision (JJV) had announced a $36.35 million first-of-its-kind public-private partnership in Asia to tackle myopia. Key focus areas of this partnership include developing predictive tools to identify those who may be at risk of developing high myopia and conducting research on the underlying mechanisms of myopia.
diabetes.jpg SGH and Duke-NUS Researchers Discover New Method to Grow Skin in Lab
A team of researchers from Duke-NUS Medical School and the Singapore General Hospital (SGH) found that specific laminin proteins LN-511 or LN-421 are used as a supportive cell culture matrix and have been found to support the growth of human keratinocytes in a similar way for treatment of severe burns.