National Large Animal Research Facility
The National Large Animal Research Facility (NLARF) is a joint collaboration between two Academic Medical Centres – SingHealth and National University Health System (NUHS). It is supported by a National Research Foundation (NRF) grant, which is administered by the National Medical Research Council (NMRC). The development and operation of NLARF is overseen by a Joint Governing Board with representatives from NMRC, SingHealth and NUHS. The Research, Innovation and Enterprise (RIE) 2020 planning exercise reiterates its importance in Singapore's biomedical research community.
Located in Northwest Singapore, NLARF operates a large animal-based research and housing facility which is licensed by the Agri-Food and Veterinary Authority (AVA). Prior to its transformation into NLARF, the predecessor facility (known as SingHealth Sembawang AH&H) was set up in 2001 and has attained its Association for Assessment and Accreditation of Laboratory Animal Care (AAALAC) International accreditation since 2006. This AAALAC Accreditation continues for the NLARF animal care and use programme.
The NLARF programme is fully equipped with international quarantine facilities for large animals, including domestic pigs, mini pigs and Non-Human Primates (NHPs). Through well-established working relationships with overseas suppliers, NLARF carries out regular imports to meet the local scientific demands for research-quality NHPs and pigs. The successful importation of an improved genetic line of pigs from the Netherlands in 2013, has allowed NLARF to supply High Health Status (HHS) pigs for Singapore.
To utilise and disburse NLARF funds in accordance with milestones mapped out to meet national objectives
To provide quality services in support of biomedical research and training with adherence to the highest international standards for humane and ethical animal care and use
The core strengths of NLARF include:
The only AVA-approved international quarantine for pigs and NHPs in Singapore
Expertise in large animal importation for scientific uses, including regulatory clearance
Competent team of professionals trained in management of large animals* for research
Research quality NHPs and pigs (local and imported)
Long-term housing of large animals in sheltered outdoor housing
NLARF also provides the following services:
Supply of large animals at age and/or weight required for research
Animal care, maintenance and emergency treatment
Technical and veterinary services for PI-initiated research
Transport services for large animals using a designated, climate-controlled vehicle
Training courses in large animal husbandry, care and basic diagnostics
Comprehensive services to meet PI’s research needs, including import of other animal models