The potency and toxicity of many drugs is dependent on the circadian phase at which the drug is administered. It is therefore important to develop clinical methods for estimating internal body time. Chronotherapeutics, the study of the impact of circadian rhythms on drug metabolism and efficacy, is a rapidly growing area in medicine. It holds the promise of delivering therapies at optimal points in the circadian cycle in terms of safety, efficacy, and tolerability.

The SingHealth IMU is uniquely positioned to utilize its Chronobiology Laboratory and subject matter expertise to both advance the science of Chronotherapeutics and provide drug developers the capability to study and enhance the chronotherapeutic properties of their compounds.